Post-operative acute kidney injury in Stanford Type A aortic dissection

Results Mean age was 52 ± 12 years. In-hospital peri-operative mortality was 12.9%. Mean aortic cross-clamp time was 124 ± 72 minutes; mean duration of deep hypothermic circulatory arrest (DHCA) was 47 ± 30 minutes. 25.8% of patients developed post-operative acute kidney injury. 6.5% required temporary renal replacement therapy. Preoperative renal impairment and presence of ischemic heart disease were significant predictors of the need for post-operative hemodialysis. Pre-operative serum creatinine level was a statistical significant risk factor of elevated serum creatinine on the 1st, 2nd and 3rd postoperative day. Duration of DHCA, cardiopulmonary bypass time and body surface area were significant predictors of elevated serum creatinine on the 1st postoperative day. Aortic cross-clamp time correlated significantly wit duration of hemodialysis (p=0.041). Presence of pre-operative renal impairment correlated significantly with the need for hemodialysis (p=0.035). Intra-operative urine output did not correlate significantly with postoperative serum creatinine (p=0.055) or the duration of hemodialysis (p=0.392).